Manchester United and Manchester City played out a goalless draw at Old Trafford overnight leaving both sides frustrated.
The pair missed out on what was an opportunity to prove their Premier League title credentials while denting the confidence of one of their main rivals.
The draw sees Manchester City move back to the top of the table, but only on goal difference with Arsenal sharing the same number of points, as United remain fourth.
Chris Smalling arguably came closest to winning the match, with his low poke at goal in the dying few minutes only kept out by a superb Joe Hart save.
It was the 50th derby draw these sides have played out, the first draw since November 2010.
Adam Johnson has inspired Sunderland to their first victory under Sam Allardyce in the tyne-wear derby, with Johnson celebrating his goal in controversial fashion.
The winger scored the opening goal of the match against Newcastle when he converted a controversially awarded penalty that saw Fabricio Coloccini sent off.
After dispatching the ball from the spot past Rob Elliot, Johnson ran the length of the pitch to celebrate in front of the away fans at the Stadium of Light.
Goals from Billy Jones and Steven Fletcher completed the 3-0 rout, giving Sunderland their sixth straight win over their rivals.
Liverpool have drawn yet again under Klopp and remain winless with the German in charge after a 1-1 draw with Southampton at Anfield.
Christian Benteke came off the bench at half-time to thump a header home from Milner's well worked cross ten minutes from time that drew a trademark celebration from Klopp on the sidelines.
Nine minutes later however, Saido Mane bundled the ball over the line from James Ward-Prowse's free-kick to spoil the party.
Klopp now has a worse record from his three matches as Liverpool manager than Brendan Rodger's last three.
In the night's other match, Tottenham thumped Bournemouth at Vitality Stadium 5-1 after going behind in the opening minute of the game.
Spurs rallied however, and Harry Kane finished with a hat-trick as well as goals for both Moussa Dembele and Erik Lamela.
Tottenham now sit sixth, while Bournemouth sit two points outside relegation.